Treatment included strict elimination of peanuts and tree nuts from diet and self-injectable adrenaline. ImmunoCAP Specific for latex molecular allergens (Hev b 9, Hev b 11, Hev b 6.02, Hev b 6.01, Hev b 5, Hev b 3, and Hev b 1) was performed, which confirmed positivity only for Hev b 3 (2.31 kU/L).Ī challenge test was performed with a latex glove: first with finger glove and then with whole glove, which were negative. For a better understanding of the clinical situation, we performed ImmunoCAP ISAC that was positive for storage proteins of walnut and hazelnut, Jug r 1 and Cor a 9, with values of 0.6 and 33 ISAC Standardized Units (ISU-E), respectively, and for a specific allergen of latex (Hev b 3: 1.9 ISU-E). Initial diagnostic exams revealed a positive skin prick test to walnut (wheal mean diameter 5 mm same as histamine diameter) and specific IgE for cashew nut 21.1 kU/L walnut 10 kU/L hazelnut 2.94 kU/L, and almond 0.46 kU/L. The previous year she had an episode of labial swelling after ingesting a chocolate with hazelnut. Also, we emphasize the importance to latex sensitization with potential future clinical relevance and the sensitization to Hev b 3, which is not documented to be involved in cross-reactivity phenomena/latex–fruit syndrome or present in an otherwise healthy child.Ī 5-year-old Caucasian girl with no significant past medical history and with a family history of allergic disease (mother and 7-year-old brother with allergic rhinitis to pollens) was referred to Pediatric/Allergology Consultation after an episode of sialorrhea, perioral urticarial rash, tongue swelling, and immediate vomiting after oral contact with cashew nut. It is interesting that anaphylaxis was the first manifestation of allergy in a healthy child. ImmunoCAP ISAC was positive for storage proteins of walnut and hazelnut (Jug r 1 e Cor a 9) and for a specific allergen of latex (Hev b 3). Investigation revealed the following: positive skin prick test to walnut and positive specific IgE for cashew nut, walnut, hazelnut, and almond. We present the case of a previous healthy 5-year-old girl referred to Pediatric/Allergology Consultation after an episode of sialorrhea, perioral urticarial rash, tongue swelling, and immediate vomiting after oral contact with cashew nut. Cross-reactivity can occur not only with foods that are in the same biological family but also between certain fruits or vegetables and latex (latex–fruit syndrome). doi:10.Food allergy affects many young children and tree nut allergy is accountable for a large number of severe, life-threatening anaphylactic reactions. When, what, and how to introduce solid foods. Poison ivy, oak, and sumac: What should I do if I touch a plant?Ĭenters for Disease Control and Prevention. Oral allergy syndrome: an update for stomatologists. The genome evolution and domestication of tropical fruit mango. Wang P, Luo Y, Huang J, Gao S, Zhu G, Dang Z, et al. Cross reactivity between papaya, mango, and cashew. doi:10.5811/cpcem.206Īmerican Academy of Allergy Asthma and Immunology. Mango Dermatitis After Urushiol Sensitization. (mango): the inestimable value of orchards recently planted in Sicilian rural areas. Multifaceted health benefits of Mangifera indica l. Lauricella M, Emanuele S, Calvaruso G, Giuliano M, D’Anneo A. Oral allergy syndrome (OAS) or pollen fruit syndrome (PFS). Oral allergy syndrome (OAS).Īmerican Academy of Allergy Asthma and Immunology. doi:10.5415/apallergy.2011.1.1.43Ĭenters for Disease Control and Prevention. Hypersensitivity manifestations to the fruit mango. Contact allergy induced by mango (mangifera indica): A relevant topic?. doi:10.1186/s1322-1Ĭamelia Berghhea E, Craiu M, Ali S, Loredana Corcea S, Silvia Bumbacea R. Anaphylactic reaction in patient allergic to mango. Ukleja-Sokołowska N, Gawrońska-Ukleja E, Lis K, Żbikowska-Gotz M, Sokołowski Ł, Bartuzi Z.
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